Cancer vaccine clinical trials: Dana-Farber has new findings using Spotfire®

As medical research continues to improve rapidly with the advance of scientific information technology, Dana-Farber has developed a novel analysis method to extract complex data for cancer vaccines from clinical trial repositories. Using TIBCO Spotfire® data visualization and summarization software, Dana-Farber researchers can now work faster and more efficiently to understand data and make decisions that are instrumental in bettering future cancer vaccine trials.

When it comes to discovering meaningful correlations and relationships across cancer vaccine clinical trials, information about trials is fairly accessible. The data is organized into categories and is easily downloaded from data collections that are curated by the ClinicalTrials.gov website and National Cancer Institute Surveillance. But the data registries are plagued by inconsistency and redundancy, making it difficult for researchers to get a good grasp on analyzing both overview and in-depth trends across available data.

Selected for its easy-to-learn, intuitive user interface and its ability to instantly create search queries or pare down data into relevant subsections, the TIBCO Spotfire platform allowed Dana-Farber researchers to complete an assessment of the cancer vaccine clinical trials market. Using Spotfire, researchers were able to look at the clinical trials from various angles to see clinical trials by timeline, type of cancer, lead institution, patient population, and specific vaccine technology. This allowed the project to reveal previously undetected patterns, trends and biases within cancer vaccine clinical trial data.

Researchers discovered that certain types of cancers, such as bladder, liver, pancreatic, stomach, esophageal and all low-incidence cancers, are lacking in volume of trials in the cancer vaccine field, highlighting areas and opportunities for improved representation of all cancers in future trials.

By using Spotfire to assess the cancer vaccine clinical trials market, Dana-Farber revealed a gap that exists between available data and the ability to properly analyze and extract information from that data. Dana-Farber’s use of Spotfire has now demonstrated that data visualization and summarization software can be used to withdraw important relationships that exist within copious data collections, which specifically in this case can be used to improve and hone future cancer vaccine clinical trials and research efforts.

Interested in learning more about TIBCO Spotfire software? You can read more and watch video demos about the Spotfire data visualization platform and the specific add-ons our PerkinElmer Informatics team is developing with the scientific community in mind: Learn more about TIBCO Spotfire.  

Or click here to read an in-depth white paper detailing Dana-Farber's use of Spotfire to assess the cancer vaccine clinical trials market.

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